Effects of Nerve Regeneration Therapy on SFI in Nerve Injured Rats
AUTHORS
Youn-Bum Sung,712-714 Dept. Physical Therapy, Daegu Univ., Jillyang-eup, Gyeongsan-si, Gyeongsangbuk-do, Republic of Korea
Jung-Ho Lee,(Corresponding Author) 219-705 Dept. Physical Therapy, Kyungdong Univ., Bongpo-ri, Toseong-myeon, Goseong-gun, Gangwon-do, Republic of Korea
ABSTRACT
The purpose of this study was to evaluate the effect of nerve regeneration therapy on SFI test after peripheral nerve crush injury in each group as time passes. The rats were randomly assigned to a control group (CG, n = 15) that would not to receive any therapeutic intervention after being affected by sciatic nerve damage, a CIMT group (CEG, n = 15) that would undergo treadmill exercises utilizing CIMT after being affected by sciatic nerve damage, and an exercise group (EG, n = 15) that would only undergo treadmill exercise after being affected by sciatic nerve damage. In addition, each group underwent SFI test at day 1, day 7, and day 14 after receiving treatment. As a result of this study, there was no statistically significant difference in all groups at 7 days, but there was a significant difference at 14 days. The post hoc test showed significant differences among all groups at 14 days. Significant differences were found between CEG and EG, EG and CG. This result shows that exercise after peripheral nerve injury is better, and it is better to apply CIMT and exercise than that. These results suggest that sensory fibers and motor fibers were effectively regenerated and re-innervated thanks to the stimulation of cell healing based on the principle of sensory motor integration therapy to improve functional activities.
KEYWORDS
Nerve Regeneration Therapy, Sciatic Functional Index, Rat, Nerve injury
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